The effects of various chemotherapy on about 100 cases of pulmonary tuberculosis
were compared, and the following results were obtained.
1. When the antituberculous agent is used in large dosage at the beginning of
therapy, the bacteriological effect is more prominent.
2. Regimen of combination of four antituberculous drugs showed no better results than
the triple therapy.
3. In cases with hard-to-heal tuberculous lesions, on ghoul antituberculous drugs had
been used in sufficient amounts the use of large dosage of INH in SM+PAS+INH
regimen, INH+CS regimen, or INH+CS+PAS regimen (CS=Cycloserine)was most
effective.
4. In case of repeated hemoptysis during the use of INH, replacement with Reazide is
effective.
5 Among seven cases of open healing of cavities, four has been engaged in works for
more than a year´ without recurrence.
6. Rest during chemotherapy is more necessary when the tubercle bacilli are drug
resistant.
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